Osphos for the Treatment of Navicular Disease

Osphos is an injectable bisphosphonate used for the control of clinical signs associated with navicular disease in horses 4 years and older. Bisphosphonates are a class of drug commonly prescribed to prevent bone loss in people. The exact mechanism of action in horses is not quite fully understood but what we know is that Clondronate, the active ingredient in Osphos is a bisphonate that is known to inhibit bone resorption thereby ultimately decreasing the breakdown of bone.

Navicular syndrome is known to cause stress and damage to the naviculal bone leading to excessive bone remodeling. Bone remodeling is a balanced pathway between bone resorption and bone rebuilding. A disruption in balance results in more bone being resorbed than built which can occur with the many factors involved in navicular disease. Osphos helps maintain the balance to be coordinated and equal.

What can you expect?
An intra muscular injection of one vial of Osphos. Typical results of improved lameness scale between 1 and 3 grades better last at least 6 months or more. For those horses that maintain clinical improvement less than 6 months intervals for injection can be 3-6 months apart.

Some horses may appear agitated post injection usually hand walking for 15-20 minutes help alleviate these signs. Some horses may experience colic signs, cramping, nervousness as well. Making sure the horse is properly hydrated, rested and in good health is important prior to administration. Annual blood work is recommended to check for liver and kidney function prior to administration is also recommended.

If you are interested in learning more about this product feel free to call me at 949-290-0881 or email silviacolladay@yahoo.com. You can also visit the Dechra friendly website at www.osphos.com to learn more about this product!

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